Name | Dimethylamine hydrochloride |
Synonyms | Dimethylamine HCl dimethylammonium chloride DiMethylaMine hydrochlorid Dimethylamine hydrochloride hydrochloricaciddimethylamine n-methylmethanaminehydrochloride n-methyl-methanaminhydrochloride Methanamine,N-methyl-,hydrochloride |
CAS | 506-59-2 |
EINECS | 208-046-5 |
InChI | InChI=1/C2H7N.ClH/c1-3-2;/h3H,1-2H3;1H |
InChIKey | IQDGSYLLQPDQDV-UHFFFAOYSA-N |
Molecular Formula | C2H8ClN |
Molar Mass | 81.54 |
Density | 0.8949 (rough estimate) |
Melting Point | 170-173°C(lit.) |
Boling Point | 95.79°C (rough estimate) |
Water Solubility | 3000 g/L (20 ºC) |
Solubility | Easily soluble in water, soluble in ethanol and chloroform, almost insoluble in ether |
Vapor Presure | <0.1 hPa (25 °C) |
Appearance | White crystal |
Color | White to off-white |
Merck | 14,3228 |
BRN | 3589311 |
PH | 5 (100g/l, H2O, 20℃) |
Storage Condition | Store below +30°C. |
Stability | Stable. Incompatible with strong oxidizing agents. |
Sensitive | Hygroscopic |
Refractive Index | 1.4202 (estimate) |
MDL | MFCD00012477 |
Physical and Chemical Properties | Melting point 160°C water-soluble 3000g/L (20°C) |
Use | Used as a catalyst for acetylation analysis, but also for organic synthesis and the preparation of aqueous dimethylamine solutions |
Hazard Symbols | Xn - Harmful |
Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. |
WGK Germany | 1 |
RTECS | IQ0220000 |
FLUKA BRAND F CODES | 3-9 |
TSCA | Yes |
HS Code | 29211190 |
Toxicity | LD50 in mice (g/kg): 1.21 i.v., 2.00 s.c. (Hazard); LC50 in mice (ppm): 7650 (48 hr), 4725 (14 day); in rats (ppm): 4540 (6 hr) (Steinhagen) |
LogP | -3.28 |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
Use | Dimethylamine hydrochloride is a raw material for organic synthesis, and is also used as a catalyst for acetylation analysis and preparation of magnesium reagent and dimethylamine aqueous solution. Dimethylamine hydrochloride has strong deoxidation ability and strong corrosiveness, so it is often used for cleaning flux. high activity, can reduce the surface tension, so that the solder and the metal to be welded wetting each other, enhance the ability of soldering; organic analysis reagents, acetylation analysis as a catalyst, also used in organic synthesis and preparation of dimethylamine aqueous solution. Dimethylamine hydrochloride is a raw material for organic synthesis, and is also used as a catalyst and magnesium reagent for acetylation analysis. Used as a catalyst for acetylation analysis, and also used in organic synthesis and preparation of dimethylamine aqueous solution Used as a raw material for pharmaceuticals |
toxicological data | acute toxicity: rat oral LD50:1070mg/kg; Mouse oral LD50:8100mg/kg; Mouse intraperitoneal LD50:1570mg/kg; Mouse subcutaneous LD50:2gm/kg; Mouse intravenous LD50:1210mg/kg; Rabbit oral LD50:1600mg/kg; guinea pig oral LD50:1600mg/kg. Reproductive toxicity: mice transabdominal TDLo: female pregnancy 1-17 days after pregnancy: 3825mg/kg; Affect the mortality rate after embryo implantation. Tumor data: mouse oral TDLo:12 gm/kg/Y-C, RTECS standard for tumor, lung, chest or respiratory-bronchial cancer liver-tumor. |
Production method | It is obtained by salting dimethylamine and hydrochloric acid. Slowly drip hydrochloric acid into dimethylamine, the dosage of hydrochloric acid 30% is about 1.1 times that of 40% dimethylamine, and the drip speed is limited to the temperature not exceeding 15 ℃ and pH = 7-8. After the reaction, add activated carbon to decolorize, filter, adjust the filtrate to pH = 3-4 with hydrochloric acid, and evaporate water under reduced pressure to the end to obtain dimethylamine hydrochloride. |